4-Chloro-3-nitrobenzoyl chloride → N-(4-Bromo-3-fluoro-phenyl)-4-chloro-3-nitro-benzamide

HRID 605063Notes

Reaction equation

HRID 605063 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[Br:14][C:15]1[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][C:16]=1[F:22]>>[Br:14][C:15]1[CH:20]=[CH:19][C:18]([NH:21][C:6](=[O:7])[C:5]2[CH:9]=[CH:10][C:2]([Cl:1])=[C:3]([N+:11]([O-:13])=[O:12])[CH:4]=2)=[CH:17][C:16]=1[F:22]

Participants

3

Reactant 2

HCID 1234774-Chloro-3-nitrobenzoyl chlorideHCID 8218484-Bromo-3-fluoroaniline

Product 1

HCID 65436917N-(4-Bromo-3-fluoro-phenyl)-4-chloro-3-nitro-benzamide

Procedure

A mixture of 4-chloro-3-nitrobenzoyl chloride was reacted with 4-Bromo-3-fluoro-phenylamine to produce N-(4-Bromo-3-fluoro-phenyl)-4-chloro-3-nitro-benzamide according to the procedure of Example 10A, which was treated sequentially using the procedures from Examples 13A, 13B and 13C to provide the title product.

Sources & evidence

ORD record
ord-469aa1ddd83f4b2bb8dcf6b4d0194b78
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

Loading…