4-Chloro-3-nitrobenzoyl chloride → HCID 67040847, compound

HRID 605073Notes

Reaction equation

HRID 605073 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[Br:14][C:15]1[CH:16]=[N:17][C:18]([NH2:21])=[N:19][CH:20]=1>>[Br:14][C:15]1[CH:16]=[N:17][C:18]([NH:21][C:6](=[O:7])[C:5]2[CH:9]=[CH:10][C:2]([Cl:1])=[C:3]([N+:11]([O-:13])=[O:12])[CH:4]=2)=[N:19][CH:20]=1

Participants

3

Reactant 2

HCID 1234774-Chloro-3-nitrobenzoyl chlorideHCID 2313102-Amino-5-bromopyrimidine

Product 1

HCID 67040847HCID 67040847, compound

Procedure

A mixture of 4-chloro-3-nitrobenzoyl chloride was reacted with 5-Bromo-pyrimidin-2-ylamine to produce N-(5-Bromo-pyrimidin-2-yl)-4-chloro-3-nitro-benzamide according to the procedure of Example 10A, which was treated sequentially using the procedures from Examples 22A and 22B to provide the title product.

Sources & evidence

ORD record
ord-43687c87e5b84e97ba8c664af484005d
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

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