HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide dimethyl acetal → N'-(3-Cyano-pyridin-2-yl)-N,N-dimethyl-formamidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 2-Amino-3-cyanopyridine | HCID 818259 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N'-(3-Cyano-pyridin-2-yl)-N,N-dimethyl-formamidine | HCID 66808319 | 100% |
Reaction Steps
A solution of 2-Amino-nicotinonitrile (5 g, 42 mmol) and N,N-Dimethylformamide dimethyl acetal (6.13 mL, 46.2 mmol) in toluene (20 mL) was heated at reflux for 3 hours. After cooling to room temperature, the solution was concentrated under vacuum to provide the title compound (7.3 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910595B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-56ebdd2875d743dfb4060ea66f2176df |
| Source note | uspto-grants-2011_03 |