2-Fluoroaniline → HCID 2841903, compound

HRID 605111Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[F:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[NH2:21]>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:21][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[F:14])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12]

Participants

Reactant 2

HCID 95842-Fluoroaniline

HCID 1234774-Chloro-3-nitrobenzoyl chloride

Product 1

HCID 2841903HCID 2841903, compound

Procedure

A mixture of 4-chloro-3-nitrobenzoyl chloride was reacted with 2-Fluoro-phenylamine to produce 4-Chloro-N-(2-fluoro-phenyl)-3-nitro-benzamide according to the procedure of Example 10A, which was treated sequentially using the procedures from Examples 22A and 22B to provide the title product.

Sources & evidence

ORD record: ord-47cf6b81ee764cfa8678f62f6bd3f712
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07910595B2

Reaction notes

Loading…