3-Fluoroaniline → HCID 773684, compound

HRID 605112Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[F:14][C:15]1[CH:16]=[C:17]([NH2:21])[CH:18]=[CH:19][CH:20]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:21][C:17]2[CH:18]=[CH:19][CH:20]=[C:15]([F:14])[CH:16]=2)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12]

Participants

Reactant 2

HCID 97423-Fluoroaniline

HCID 1234774-Chloro-3-nitrobenzoyl chloride

Product 1

HCID 773684HCID 773684, compound

Procedure

A mixture of 4-chloro-3-nitrobenzoyl chloride was reacted with 3-Fluoro-phenylamine to produce 4-Chloro-N-(3-fluoro-phenyl)-3-nitro-benzamide according to the procedure of Example 10A, which was treated sequentially using the procedures from Examples 22A and 22B to provide the title product.

Sources & evidence

ORD record: ord-f09242c22bb3469688be52e3c8c3ca9e
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07910595B2

Reaction notes

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