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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 605130Generated: October 26, 2026

3-(Trifluoromethyl)aniline → 4-Fluoro-3-nitro-N-(3-trifluoromethyl-phenyl)-benzamide

https://huagongshe.com/reaction/605130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)anilineHCID 7375—
Reactant4-Fluoro-3-nitrobenzoyl chlorideHCID 2783347—
Product4-Fluoro-3-nitro-N-(3-trifluoromethyl-phenyl)-benzamideHCID 67040751—

Reaction Steps

A mixture of the product from Example 86A was reacted with 3-Trifluoromethyl-phenylamine to produce 4-Fluoro-3-nitro-N-(3-trifluoromethyl-phenyl)-benzamide according to the procedure of Example 86B, which was treated sequentially using the procedures from Examples 86C and 86D to provide the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07910595B2
Source datasetuspto-grants-2011_03
ORD IDord-80f4e491a7fd46078ee6334dead70bba
Source noteuspto-grants-2011_03