3-Fluoro-4-methylaniline → HCID 26415777, compound

HRID 605149Notes

Reaction equation

HRID 605149 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([NH2:9])[CH:5]=[CH:6][C:7]=1[CH3:8].[Cl:10][C:11]1[CH:19]=[CH:18][C:14]([C:15](Cl)=[O:16])=[CH:13][C:12]=1[N+:20]([O-:22])=[O:21]>>[Cl:10][C:11]1[CH:19]=[CH:18][C:14]([C:15]([NH:9][C:4]2[CH:5]=[CH:6][C:7]([CH3:8])=[C:2]([F:1])[CH:3]=2)=[O:16])=[CH:13][C:12]=1[N+:20]([O-:22])=[O:21]

Participants

3

Reactant 2

HCID 99573-Fluoro-4-methylanilineHCID 1234774-Chloro-3-nitrobenzoyl chloride

Product 1

HCID 26415777HCID 26415777, compound

Procedure

A mixture of 3-Fluoro-4-methyl-phenylamine was reacted with 4-chloro-3-nitrobenzoyl chloride using the procedure of Example 10A to provide 4-Chloro-N-(3-fluoro-4-methyl-phenyl)-3-nitro-benzamide which was reacted according to the conditions described in Examples 100A, 100B, and 100C to provide the title product.

Sources & evidence

ORD record
ord-d75035927b3a47feaa775c7b7d16aaf8
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

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