1,3,4-Thiadiazol-2-amine → HCID 67040940, compound

HRID 605194Notes

Reaction equation

HRID 605194 reaction equation
[Cl:1][C:2]([Cl:28])([Cl:27])[CH2:3][O:4][C:5](=[O:26])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](Cl)=[O:21])=[CH:16][C:15]=2[N+:23]([O-:25])=[O:24])=[CH:9][CH:8]=1.[S:29]1[CH:33]=[N:32][N:31]=[C:30]1[NH2:34]>C1(C)C=CC=CC=1>[Cl:1][C:2]([Cl:28])([Cl:27])[CH2:3][O:4][C:5](=[O:26])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:21])[NH:34][C:30]3[S:29][CH:33]=[N:32][N:31]=3)=[CH:16][C:15]=2[N+:23]([O-:25])=[O:24])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 199091,3,4-Thiadiazol-2-amineHCID 86615557HCID 86615557, compound

Product 1

HCID 67040940HCID 67040940, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The product of Example 162b (300 mg, 0.6197 mmol) and [1,3,4]Thiadiazol-2-ylamine (62 mg, 0.6197 mmol) in toluene (10 mL) were reacted as in Example 162c to yield the title compound (340 mg, 100% yield).

Sources & evidence

ORD record
ord-1e805f8f883c4438ac5b39518fe10d48
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

Loading…