1,3,4-Thiadiazole, 2-amino-5-methyl- → HCID 67041035, compound

HRID 605211Notes

Reaction equation

HRID 605211 reaction equation
[Cl:1][C:2]([Cl:28])([Cl:27])[CH2:3][O:4][C:5](=[O:26])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](Cl)=[O:21])=[CH:16][C:15]=2[N+:23]([O-:25])=[O:24])=[CH:9][CH:8]=1.[CH3:29][C:30]1[S:34][C:33]([NH2:35])=[N:32][N:31]=1>C1(C)C=CC=CC=1>[Cl:1][C:2]([Cl:28])([Cl:27])[CH2:3][O:4][C:5](=[O:26])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:21])[NH:35][C:33]3[S:34][C:30]([CH3:29])=[N:31][N:32]=3)=[CH:16][C:15]=2[N+:23]([O-:25])=[O:24])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 669491,3,4-Thiadiazole, 2-amino-5-methyl-HCID 86615557HCID 86615557, compound

Product 1

HCID 67041035HCID 67041035, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of Example 162b (300 mg, 0.6197 mmol) and 5-Methyl-[1,3,4]thiadiazol-2-ylamine (71 mg, 0.6197 mmol) in toluene (10 mL) was reacted as in Example 162c to give the title compound as a yellow powder.

Sources & evidence

ORD record
ord-3668d9a967a748df94c91037ecd77850
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

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