HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → Thiophene-2-carboxylic acid [3-amino-4-(4-hydroxy-phenylsulfanyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Thiophene-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-nitro-phenyl]-amide | HCID 67040141 | — |
| Catalyst | Iron | HCID 23925 | — |
| Product | Thiophene-2-carboxylic acid [3-amino-4-(4-hydroxy-phenylsulfanyl)-phenyl]-amide | HCID 67040212 | 52% |
Reaction Steps
The product from Example 240b was reduced with Fe and NH4Cl following the procedure from Example 9E to provide the title compound (800 mg, 52%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910595B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-a6ef51c2520f4d5d9f90e4dd21d41a66 |
| Source note | uspto-grants-2011_03 |