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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 605270Generated: October 30, 2026

Water → HCID 789035, compound

https://huagongshe.com/reaction/605270

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant4-Fluoro-3-nitroanilineHCID 67768—
Reactant2-Furancarbonyl chlorideHCID 68242—
ReactantDiisopropylethylamineHCID 81531—
SolventTetrahydrofuranHCID 8028—
ProductHCID 789035HCID 78903590.5%

Reaction Steps

The title compound was synthesized from 4-fluoro-3-nitro-phenylamine (2.00 g, 12.81 mmol) dissolved in THF (25 ml) and Hunig's base (3.312 g, 25.62 mmol) to which was added furan-2-carbonyl chloride (1.672 g, 12.81 mmol) drop wise over 10 minutes. Reaction mixture was stirred at room temperature for 1 hr at which time water was added and the title compound was collected by filtration providing the title compound (2.90 g, 90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07910595B2
Source datasetuspto-grants-2011_03
ORD IDord-483266bf294241a1884837a0649c6159
Source noteuspto-grants-2011_03