反应详情

A mixture of 5-chloro-2-methyl-4-nitrophenylamine (0.475 g, 2.55 mmol) and phenylacetyl chloride (0.394 g, 2.55 mmol) in toluene (10 mL) was heated under reflux for 4 h, then cooled to room temperature. A solid crystallized from the reaction mixture upon cooling, and was isolated by vacuum filtration and dried to provide the title compound as a yellow solid (0.330 g, 43%).

1. temperaturewas heated
2. temperatureunder reflux for 4 h
3. customA solid crystallized from the reaction mixture
4. temperatureupon cooling
5. customwas isolated by vacuum filtration
6. customdried