Aniline → HCID 67040565, compound

HRID 605315Notes

Reaction equation

HRID 605315 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=2[N+:17]([O-])=O)=[CH:4][CH:3]=1.[NH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.BrC1C=C(C=CC=1)N>>[C:21]1([NH:20][C:14]([C:12]2[S:13][C:9]([S:8][C:5]3[CH:4]=[CH:3][C:2]([OH:1])=[CH:7][CH:6]=3)=[C:10]([NH2:17])[CH:11]=2)=[O:16])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 115623-BromoanilineHCID 670406395-(4-Hydroxy-phenylsulfanyl)-4-nitro-thiophene-2-carboxylic acid

Product 1

HCID 67040565HCID 67040565, compound

Procedure

The product from Example 351C was reacted with aniline according to the procedure of Example 351D substituting aniline for 3-bromoaniline followed by reduction of the nitro group according to the procedure from Example 351E to provide the title product.

Sources & evidence

ORD record
ord-5fe296596ba04bd0bf8eb012fbebeb2a
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

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