反应详情

To a solution of (S)-1-(1-azidoethyl)-2-bromobenzene (45 mg, 0.2 mmol) in EtOH/H2O (5 mL/5 mL) was added in NH4Cl (108 mg, 2.0 mmol) and indium (91 mg, 0.8 mmol). The mixture was refluxed overnight. The reaction mixture was filtered, washed with EtOH and evaporated. The residue was triturated with AcOEt and filtered. The filtrate was evaporated to give the title compound (35 mg, 88%).

1. temperatureThe mixture was refluxed overnight
2. filtrationThe reaction mixture was filtered
3. washwashed with EtOH
4. customevaporated
5. customThe residue was triturated with AcOEt
6. filtrationfiltered
7. customThe filtrate was evaporated