HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-tert-Butoxycarbonylamino-phenylsulfanyl)-3-nitro-benzoic acid methyl ester → Methyl 3-amino-4-(4-(methoxycarbonylamino)phenylthio)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-tert-Butoxycarbonylamino-phenylsulfanyl)-3-nitro-benzoic acid methyl ester | HCID 59376870 | — |
| Reactant | Methyl 4-(4-(methoxycarbonylamino)phenylthio)-3-nitrobenzoate | HCID 67041007 | — |
| Product | Methyl 3-amino-4-(4-(methoxycarbonylamino)phenylthio)benzoate | HCID 67040749 | 88% |
Reaction Steps
The title compound was prepared by the procedure in Example 385C substituting the product from Example 441A for the product of Example 385B. The reaction was purified by silica gel chromatography (ethyl acetate/CHCl3=1/9) to give the title compound (yield 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910595B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-e156897df9164f93ad499a016bae9f56 |
| Source note | uspto-grants-2011_03 |