HCID 67040380, compound → HCID 67040575, compound

Participants

Reaction Steps

The title compound was prepared (yield 89%) by the procedure in Example 385G substituting the product of Example 446A for the product of Example 385F. 1H-NMR (300 MHz, DMSO-d6) δ ppm: 1.33 (d, J=7.0 Hz, 6H), 1.86-2.04 (m, 1H), 2.33-2.53 (m, 1H), 2.74-3.03 (m, 2H), 3.22 (septet, J=7.0 Hz, 1H), 5.48-5.62 (m, 1H), 5.58 (s, 2H), 6.62 (d, J=8.5 Hz, 2H), 6.83 (d, J=8.1 Hz, 1H), 7.11-7.28 (m, 4H), 7.13 (d, J=8.5 Hz, 2H), 7.63 (d, J=8.5 Hz, 1H), 7.75 (dd, J=8.1, 1.5 Hz, 1H), 7.90 (d, J=1.5 Hz, 1H), 8.56 (s, 1H), 8.73 (d, J=8.1 Hz, 1H), 8.86 (d, J=8.5 Hz, 1H), 10.11 (s, 1H) MS ESI+ m/z: 547 (M+H), ESI− m/z: 545 (M−H)

Provenance & Evidence