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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 605824Generated: November 1, 2026

HCID 57507805, compound → HCID 57507806, compound

https://huagongshe.com/reaction/605824

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57507805HCID 57507805—
ReactantHCID 178418361HCID 178418361—
CatalystHCID 178418390HCID 178418390—
SolventTetrahydrofuranHCID 8028—
ProductHCID 57507806HCID 5750780634.4%

Reaction Steps

10% Palladium-carbon (catalytic amount) was added to a THF (10 ml) solution containing 5-[({4-[4-(benzyloxy)phenoxy]piperidin-1-yl}carbonyl)oxy]nicotinic acid (200 mg), and in a hydrogen gas atmosphere, this was stirred at room temperature under normal pressure for 3 hours. The catalyst was removed by filtration, and the resulting filtrate was concentrated under reduced pressure to obtain 5-[({4-[4-(hydroxy)phenoxy]piperidin-1-yl}carbonyl)oxy]nicotinic acid (55 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07915261B2
Source datasetuspto-grants-2011_03
ORD IDord-51bc84fe513e4e24a10fdb6d768bc9d4
Source noteuspto-grants-2011_03