Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-(Pyrimidin-4-yl)benzoic acid hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Methyl 2-(pyrimidin-4-yl)benzoate | HCID 86680852 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-(Pyrimidin-4-yl)benzoic acid hydrochloride | HCID 86680853 | — |
반응 단계
A mixture of methyl 2-(pyrimidin-4-yl)benzoate (0.49 g), acetic acid (2.0 mL) and 6 N hydrochloric acid (10 mL) was heated under reflux for 5 hr. The solvent was evaporated under reduced pressure, and the obtained residue was washed with ethyl acetate to give the title compound (0.45 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09440990B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-64ad8669fdd7422f8bff69f46dec81c0 |
| 출처 메모 | uspto-grants-2016_09 |