HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4,5,5-Tetramethyl-2-(thiophen-3-yl)-1,3,2-dioxaborolane → (4-Morpholin-4-ylphenyl)-(5-thiophen-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4,5,5-Tetramethyl-2-(thiophen-3-yl)-1,3,2-dioxaborolane | HCID 2760597 | — |
| Reactant | (5-Bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine | HCID 57589931 | — |
| Product | (4-Morpholin-4-ylphenyl)-(5-thiophen-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)amine | HCID 24888777 | — |
Reaction Steps
This compound may be prepared using methods as described for Compound 120, using (5-bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine and 4,4,5,5-tetramethyl-2-thiophen-3-yl-[1,3,2]dioxaborolane in step 4. LCMS: Rt 1.19 min (95%), m/z (ESI) 379 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915256B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-4923b97bbeaf4d0283e63fe4266baee9 |
| Source note | uspto-grants-2011_03 |