HRID606003

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)N1CCN(c2ccc(Nc3ncc(Br)n4ncnc34)cc2C(F)(F)F)CC1

HCID86619667

未命名化合物

结构：c1nc2c(Nc3ccc(N4CCN(CC5CC5)CC4)cc3)ncc(-c3cn[nH]c3)n2n1

HCID135900377

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCN(c2ccc(Nc3ncc(-c4cn[nH]c4)n4ncnc34)cc2C(F)(F)F)CC1

HCID135979631

未命名化合物

PROCEDURE

实验过程

This compound may be prepared using methods as described for Compound 46, using (5-bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-[4-(4-isopropylpiperazin-1-yl)-3-trifluoromethylphenyl]amine. LCMS: Rt=0.99 (95%), m/z (ESI) 472 (M+H)+.

WORKUP

后处理

customThis compound may be prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ada7c0476ba240e586dd4f75ea8abaa3
来源数据集: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07915256B2
来源说明: uspto-grants-2011_03

反应 SMILES

C1(CN2CCN(C3[CH:16]=[CH:15][C:14]([NH:17][C:18]4[C:19]5[N:20]([N:29]=[CH:30][N:31]=5)[C:21]([C:24]5[CH:25]=[N:26][NH:27][CH:28]=5)=[CH:22][N:23]=4)=CC=3)CC2)CC1.BrC1N2N=CN=C2C(NC2C=C[C:46]([N:49]3[CH2:54][CH2:53][N:52]([CH:55]([CH3:57])[CH3:56])[CH2:51][CH2:50]3)=[C:45]([C:58]([F:61])([F:60])[F:59])[CH:44]=2)=NC=1>>[CH:55]([N:52]1[CH2:53][CH2:54][N:49]([C:46]2[CH:16]=[CH:15][C:14]([NH:17][C:18]3[C:19]4[N:20]([N:29]=[CH:30][N:31]=4)[C:21]([C:24]4[CH:25]=[N:26][NH:27][CH:28]=4)=[CH:22][N:23]=3)=[CH:44][C:45]=2[C:58]([F:61])([F:60])[F:59])[CH2:50][CH2:51]1)([CH3:57])[CH3:56]