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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 606134Generated: October 30, 2026

1,1,1-Trimethoxybutane → HCID 67041319, compound

https://huagongshe.com/reaction/606134

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-TrimethoxybutaneHCID 123512—
ReactantPyridinium chlorideHCID 10176127—
ReactantHCID 86247649HCID 86247649—
ProductHCID 67041319HCID 6704131984.5%

Reaction Steps

The methods of Part H of Example 35 were used to treat N4-[(5-pyridin-3-ylisoxazol-3-yl)methyl]quinoline-3,4-diamine (0.95 g, 2.98 mmol) with trimethy orthobutyrate (0.57 mL, 3.6 mmol) and pyridine hydrochloride (0.069 g, 0.60 mmol) and purify the product to provide 0.930 g of 2-propyl-1-[(5-pyridin-3-ylisoxazol-3-yl)methyl]-1H-imidazo[4,5-c]quinoline as a tan solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07915281B2
Source datasetuspto-grants-2011_03
ORD IDord-ae8b79aa40a04ac4a2e150328b1e2d5d
Source noteuspto-grants-2011_03