1-Acetylpiperazine → 4-acetyl-piperazine-1-carboxylic acid 5-furan-2-yl-isoxazol-3-ylmethyl Ester

Participants

Reaction Steps

To a solution of 30 mg of imidazole-1-carboxylic acid 5-furan-2-yl-isoxazol-3-ylmethyl ester in 1 mL of methylene chloride was added 16 mg of 1-piperazin-1-yl-ethanone. After stirring at room temperature for 4 hrs, the reaction mixture was concentrated under reduced pressure. The concentrate was purified by column chromatography to afford 30 mg of the title compound. (Yield: 79%).

Provenance & Evidence