HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 4-Acetyl-6-methoxy-1H-2-benzopyran-1,3(4H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 2-(Carboxymethyl)-4-methoxybenzoic acid | HCID 11816626 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 4-Acetyl-6-methoxy-1H-2-benzopyran-1,3(4H)-dione | HCID 57893130 | — |
Reaction Steps
Pyridine (5.0 ml, 62 mmol) is added slowly to suspension of 2-carboxymethyl-4-methoxy-benzoic acid (10 g, 48 mmol) in acetic anhydride (80 ml) at 0° C. After stirring for 16 h, ether (100 ml) is added. The resulting solid is collected and dried to give 10 g of 4-acetyl-6-methoxy-isochroman-1,3-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915288B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-100e4ec9f2d94fe5bf6cae32845a2666 |
| Source note | uspto-grants-2011_03 |