HCID 86209430, compound → Trifluoro-methanesulfonic acid 2H-chromen-7-yl ester

HRID 606340Notes

Reaction equation

HRID 606340 reaction equation
[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([O:13][S:14]([C:17]([F:20])([F:19])[F:18])(=[O:16])=[O:15])[CH:8]=[CH:9][C:10]=1[CH:11]=[CH2:12])C=C>ClCCl>[O:4]1[C:5]2[C:10](=[CH:9][CH:8]=[C:7]([O:13][S:14]([C:17]([F:18])([F:19])[F:20])(=[O:15])=[O:16])[CH:6]=2)[CH:11]=[CH:12][CH2:1]1

Participants

3

Reactant 1

HCID 86209430HCID 86209430, compound

Product 1

HCID 86209431Trifluoro-methanesulfonic acid 2H-chromen-7-yl ester

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of trifluoro-methanesulfonic acid 3-allyloxy-4-vinyl-phenyl ester (0.68 g, 2.2 mmol) in dichloromethane (5 ml) was added Ru-catalyst (Grubb's catalyst) (36 mg, 2 mol %), and the reaction mixture was stirred for 2 h at room temperature. After that period the reaction was complete (GC) and the reaction mixture was used in the next step without any work-up. Analytical sample was obtained after removal of the solvent by silica gel column chromatography (EA:Hex, 1:20).

Workup

  1. waitAfter that period the reaction was complete
  2. customAnalytical sample was obtained
  3. customafter removal of the solvent by silica gel column chromatography (EA:Hex, 1:20)

Sources & evidence

ORD record
ord-32f605963b474683b6e111e61f037be3
Source dataset
uspto-grants-2011_03
Patent number
US07915295B2

Reaction notes

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