HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,8-Difluoro-2H-chromene → 8-Bromo-5-fluoro-2H-chromene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,8-Difluoro-2H-chromene | HCID 22482814 | — |
| Reactant | 1-Bromo-4-fluoro-2-[(prop-2-yn-1-yl)oxy]benzene | HCID 22482847 | — |
| Product | 8-Bromo-5-fluoro-2H-chromene | HCID 22482810 | — |
Reaction Steps
This compound was prepared analogously to 5,8-difluoro-2H-chromene but using (15 g, 65 mmol) of 1-bromo-4-fluoro-2-prop-2-ynyloxybenzene to give the title compound (3.7 g, 25
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915295B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-03ea10ea4c5547c985c455aeccf266e3 |
| Source note | uspto-grants-2011_03 |