HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,8-Difluoro-2H-chromene → 5,7-Difluoro-2H-chromene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,8-Difluoro-2H-chromene | HCID 22482814 | — |
| Reactant | 1,3-Difluoro-5-(prop-2-yn-1-yloxy)benzene | HCID 22482850 | — |
| Product | 5,7-Difluoro-2H-chromene | HCID 22482855 | 23% |
Reaction Steps
This compound was prepared analogously to 5,8-difluoro-2H-chromene but using (18 g, 107 mmol) of 1,3-difluoro-5-prop-2-ynyloxybenzene and PEG-200 as solvent to give the title compound (4 g, 23%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915295B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-e78e04dc8f4c4d84967c3e134141c6ee |
| Source note | uspto-grants-2011_03 |