Sulfuric Acid → HCID 14958697, compound

HRID 606368Notes

Reaction equation

HRID 606368 reaction equation
[C:1]([C:3]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[CH:9]=1)=[CH:4][C:5]([O-:7])=[O:6])#N.[K+].S(=O)(=O)(O)[OH:17]>C(O)=O>[CH3:14][C:10]1[CH:9]=[C:8]([C:3]2[C:1](=[O:17])[O:6][C:5](=[O:7])[CH:4]=2)[CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 67046696HCID 67046696, compound

Product 1

HCID 14958697HCID 14958697, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

A suspension of potassium 3-cyano-3-(3-methylphenyl)-acrylate (0.69 g, 3 mmol), in 88% formic acid (14 ml) containing concentrated sulphuric acid (2 ml) was stirred at reflux and monitored by LC-MS until the starting material was consumed. The reaction mixture was cooled to room temperature and poured into ice/water. The resulting precipitate was recovered by filtration, washed with water (15 ml), heptane (15 ml) and air dried.

Workup

  1. temperatureat reflux
  2. customwas consumed
  3. additionpoured into ice/water
  4. filtrationThe resulting precipitate was recovered by filtration
  5. washwashed with water (15 ml), heptane (15 ml) and air
  6. customdried

Sources & evidence

ORD record
ord-846e971299b046ee8ef27905903a57d5
Source dataset
uspto-grants-2011_03
Patent number
US07915304B2

Reaction notes

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