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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 606408Generated: October 30, 2026

Ethyl 4-oxo-5-(3-thienyl)-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxylate → HCID 178522987, compound

https://huagongshe.com/reaction/606408

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-oxo-5-(3-thienyl)-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxylateHCID 57708900—
Reactant1-[2-({3-[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]propyl}oxy)pyridin-4-yl]methanamineHCID 66768769—
Reactant1-{3-[(2-([1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]oxy)ethyl)oxy}phenyl]methanamineHCID 66769099—
ReactantEthyl 4-oxo-3,4-dihydroquinazoline-2-carboxylateHCID 135437466—
ProductHCID 178522987HCID 178522987—

Reaction Steps

By a method similar to that in Example 22, and using, instead of ethyl 4-oxo-3,4-dihydro-2-quinazolinecarboxylate, ethyl 4-oxo-5-(3-thienyl)-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxylate obtained in Reference Example 65 and using, instead of 1-[2-({3-[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]propyl}oxy)pyridin-4-yl]methaneamine, 1-{3-[(2-{[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]oxy}ethyl)oxy]phenyl}methanamine obtained in Reference Example 32, the title compound was obtained as a white powder (48.0 mg, 34%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07915267B2
Source datasetuspto-grants-2011_03
ORD IDord-dfbecd2e719146d78523cb8423185ac8
Source noteuspto-grants-2011_03