Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Oxalate → Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Oxalate | HCID 7268 | — |
| 반응물 | 2-Amino-5-chlorobenzamide | HCID 78876 | — |
| 생성물 | Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate | HCID 135810262 | 58% |
반응 단계
2-Amino-5-chlorobenzamide (2.387 g) and diethyl oxalate were stirred at 175° C. for 6 hr. The mixture was allowed to cool, and the obtained crude crystals were washed with hot ethanol to give the title compound (2.051 g, 58%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07915267B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-35afc13731924c5e8c288c675a8e5e50 |
| 출처 메모 | uspto-grants-2011_03 |