1-Bromo-4-(methylsulphonyl)benzene → HCID 20100307, compound

HRID 606512Notes

Reaction equation

HRID 606512 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[C:12]([C:14]1[CH:15]=[C:16](B(O)O)[CH:17]=[CH:18][CH:19]=1)#[N:13]>>[CH3:11][S:8]([C:5]1[CH:6]=[CH:7][C:2]([C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([C:12]#[N:13])[CH:19]=2)=[CH:3][CH:4]=1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 770141-Bromo-4-(methylsulphonyl)benzeneHCID 27343253-Cyanophenylboronic acid

Product 1

HCID 20100307HCID 20100307, compound

Procedure

By a method similar to that in Example 81 and using 1-bromo-4-(methylsulfonyl)benzene and (3-cyanophenyl)boronic acid, the title compound was obtained as a pale-yellow powder (10.4 g, 95%).

Sources & evidence

ORD record
ord-bde9a97948ab40c0b548e85f4bfc6919
Source dataset
uspto-grants-2011_03
Patent number
US07915267B2

Reaction notes

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