Water → HCID 136054505, compound

Participants

Reaction Steps

To a solution of 5-({[(4-bromophenyl)methyl]thio}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one obtained in Reference Example 108 (0.500 g, 1.67 mmol) in DMF (5 mL) was added m-chloroperbenzoic acid (0.903 g, 3.67 mmol) at room temperature, and the mixture was stirred for 12 hr. Water and saturated aqueous sodium hydrogencarbonate solution were added to the reaction mixture, and the precipitated solid was collected by filtration. The solid was washed with water and diethyl ether to give the title compound as a white powder (0.508 g, 92%).

Provenance & Evidence