HCID 57708878, compound → HCID 57708877, compound

HRID 606528Notes

Reaction equation

HRID 606528 reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)N2C=NC(SCCOC3C=C(C#N)C=CN=3)=N2)C=CC=CC=1.[C:37]([N:56]1[CH:60]=[N:59][C:58]([O:61][CH2:62][C:63]2[CH:64]=[C:65]([C:69]3[CH:74]=[CH:73][CH:72]=[C:71]([C:75]#[N:76])[CH:70]=3)[CH:66]=[CH:67][CH:68]=2)=[N:57]1)([C:50]1[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=1)([C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[C:37]([N:56]1[CH:60]=[N:59][C:58]([O:61][CH2:62][C:63]2[CH:64]=[C:65]([C:69]3[CH:74]=[CH:73][CH:72]=[C:71]([CH2:75][NH2:76])[CH:70]=3)[CH:66]=[CH:67][CH:68]=2)=[N:57]1)([C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)([C:50]1[CH:51]=[CH:52][CH:53]=[CH:54][CH:55]=1)[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1

Participants

3

Reactant 2

HCID 57708878HCID 57708878, compoundHCID 66768878HCID 66768878, compound

Product 1

HCID 57708877HCID 57708877, compound

Procedure

By a method similar to that in Reference Example 20 and using, instead of 2-[(2-{[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]thio}ethyl)oxy]pyridine-4-carbonitrile, 3′-{[(1-trityl-1H-1,2,4-triazol-3-yl)oxy]methyl}biphenyl-3-carbonitrile obtained in Reference Example 134, the title compound was obtained as a colorless oil (1.12 mg, 74%).

Workup

  1. customobtained in Reference Example 134

Sources & evidence

ORD record
ord-4ebdf0437dd54f989f82ec644ec0c17f
Source dataset
uspto-grants-2011_03
Patent number
US07915267B2

Reaction notes

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