HCID 11213235, compound → HCID 11212313, compound

Participants

Reaction Steps

By following the procedure described for the preparation of 7a from 6a, 6b (46 mg, 0.11 mmol) gave 7b as a yellow solid (33 mg, 73%): [α]D−64 (c 0.25, CHCl3); IR X 2952, 1747, 1631, 1569, 1504, 1259, 1214 cm−1; 1H NMR (400 MHz, CDCl3) δ8.18 (d, J=8.2, 1H), 7.94-7.27 (m, 5H), 6.81 (d, J=6.8, 1H), 5.67 (d, J=7.3, 1H), 4.77-4.56 (m, 2H), 3.96-3.31 (m, 9H), 1.40 (m, 1H), 0.76-0.31 (m, 4H); 13C NMR (100 MHz, CDCl3) δ168.3, 161.1, 155.6149.5, 133.7, 133.7, 131.6, 128.7, 127.3, 126.4, 126.0, 125.5, 123.8, 123.4, 116.9, 115.7, 63.4, 53.5, 37.6, 32.6, 31.6, 11.8, 7.2, 7.1; HRMS (FAB+) calcd for C24H25N2O3S 421.1586, obsd 421.1593.

Provenance & Evidence