HCID 11209581, compound → HCID 11438923, compound

Participants

Reaction Steps

By following the procedure described for the preparation of 7a from 6a, 6c (36 mg, 0.11 mmol) gave 7c as a yellow solid (27 mg, 67%): [α]D−110 (c 0.13, CHCl3); IR λ 2956, 1747, 1631, 1575, 1490, 1442, 1216 cm−1; 1H NMR (400 MHz, CDCl3) δ7.49-7.30 (m, 3H), 7.25-7.15 (m, 2H), 5.64 (dd, J=8.5, 2.4, 1H), 3.92-3.69 (m, 7H), 3.62 (dd, J=11.5, 8.6, 1H), 3.41 (dd, J=11.6, 2.3, 1H), 2.02 (s, 3H); 13C NMR (100 MHz, CDCl3) δ 168.8, 161.1, 152.0, 147.8, 136.4, 130.0, 129.9, 129.0, 128.9, 128.5, 118.0, 115.3, 64.0, 53.6, 37.9, 31.7, 18.0; MS (ES+) calcd 331 for C17H20N2O3S, obsd 331.

Provenance & Evidence