3-Iodopyridine → HCID 67048332, compound

HRID 606855Notes

Reaction equation

HRID 606855 reaction equation
I[C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.[C:8]([C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=1)#[CH:9]>>[F:16][C:13]1[CH:14]=[CH:15][C:10]([C:8]#[C:9][C:2]2[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 707143-IodopyridineHCID 5226271-Ethynyl-4-fluorobenzene

Product 1

HCID 67048332HCID 67048332, compoundYield 40.6%

Procedure

Prepare essentially as described in PREPARATION 10 using 3-iodopyridine (153 mg, 0.75 mmol) and 1-ethynyl-4-fluorobenzene (100 mg, 0.83 mmol) to give the title compound (60 mg, 40%).

Workup

  1. customPrepare essentially

Sources & evidence

ORD record
ord-5f1a6cf8478045e4bacfc1b2669cbe9c
Source dataset
uspto-grants-2011_03
Patent number
US07915424B2

Reaction notes

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