Benzenamine, 3-ethynyl- → HCID 67047592, compound

HRID 606859Notes

Reaction equation

HRID 606859 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6])#[CH:2].Br[C:11]1[CH:12]=[N:13][CH:14]=[C:15]([CH:18]=1)[C:16]#[N:17]>>[NH2:6][C:5]1[CH:4]=[C:3]([C:1]#[C:2][C:11]2[CH:12]=[N:13][CH:14]=[C:15]([CH:18]=2)[C:16]#[N:17])[CH:9]=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 104682Benzenamine, 3-ethynyl-HCID 7367935-Bromonicotinonitrile

Product 1

HCID 67047592HCID 67047592, compoundYield 38%

Procedure

Prepare according to the general procedure outlined in EXAMPLE 30 using 3-ethynylaniline (1.0 g, 8.5 mmol) and 5-bromonicotinonitrile (1.56 g, 8.54 mmol) to give the title compound (0.7 g, 38%).

Workup

  1. customPrepare

Sources & evidence

ORD record
ord-bf17f1f7e9e1447095008b3ce4c250aa
Source dataset
uspto-grants-2011_03
Patent number
US07915424B2

Reaction notes

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