HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-(4-Fluorophenylethynyl)-pyridine-3-carbaldehyde O-methyloxime hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Reactant | 5-(4-Fluorophenylethynyl)-pyridine-3-carbaldehyde | HCID 86076470 | — |
| Product | 5-(4-Fluorophenylethynyl)-pyridine-3-carbaldehyde O-methyloxime hydrochloride | HCID 86622473 | 64% |
Reaction Steps
Prepare essentially as described in EXAMPLE 6 using 5-(4-fluorophenylethynyl)-pyridine-3-carbaldehyde, (prepared essentially as described in EXAMPLE 99), (150 mg, 0.64 mmol), methoxylamine hydrochloride (430 mg, 5.15 mmol) and potassium carbonate to give the title compound (120 mg, 64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-bcc5b8afadb947f28c7075d08861cc75 |
| Source note | uspto-grants-2011_03 |