HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-(4-Fluorophenylethynyl)-pyridine-3-carbaldehyde oxime hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 5-(4-Fluorophenylethynyl)-pyridine-3-carbaldehyde | HCID 86076470 | — |
| Product | 5-(4-Fluorophenylethynyl)-pyridine-3-carbaldehyde oxime hydrochloride | HCID 86622475 | 50.8% |
Reaction Steps
Prepare in a similar manner as described in EXAMPLE 6 using 5-(4-fluorophenylethynyl)-pyridine-3-carbaldehyde (150 mg, 0.64 mmol), (prepared essentially as described in EXAMPLE 99), hydroxylamine hydrochloride (360 mg, 5.15 mmol) and potassium carbonate (440 mg, 3.22 mmol) to give the title compound (90 mg, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-d059ff1a646243348ab9c23071fd09c6 |
| Source note | uspto-grants-2011_03 |