HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-2-Benzhydryl-tetrahydropyran-4-ol → Methanesulfonic acid cis-2-benzhydryl-tetrahydropyran-4-ylester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-2-Benzhydryl-tetrahydropyran-4-ol | HCID 66631792 | — |
| Reactant | methanesulfonic acid Trans-2-benzhydryl-tetrahydropyran-4-yl ester | HCID 86605343 | — |
| Product | Methanesulfonic acid cis-2-benzhydryl-tetrahydropyran-4-ylester | HCID 86605344 | 98% |
Reaction Steps
Cis-2-diphenylmethyl-4-hydroxy-pyran 3b (0.3 g, 1.12 mmol) was reacted with methanesulfonyl chloride (0.26 g, 2.24 mmol) (Procedure A) to give compound 4b (0.38 g, 98%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915433B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-b4e6d07acbd542c7832991eb183b0319 |
| Source note | uspto-grants-2011_03 |