HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → Cis-3-azido-6-benzhydryl-tetrahydropyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | Methanesulfonic acid trans-6-benzhydryl-tetra-hydropyran-3-yl ester | HCID 11566406 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Cis-3-azido-6-benzhydryl-tetrahydropyran | HCID 11630718 | 92% |
Reaction Steps
Trans-2-diphenylmethyl-tetrahydropyran-5-yl methanesulfonate 13 (0.39 g, 1.12 mmol) in dry DMF (50 ml) was reacted with sodium azide (0.22 g, 3.35 mmol) to yield cis-5-azido-2-diphenylmethyl-tetrahydropyran 14 (0.3 g, 92%) as an oil (Procedure B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915433B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-5effad5eb76f4b85ab4adc5baf4ea6c4 |
| Source note | uspto-grants-2011_03 |