HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzylamine → HCID 11417932, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzylamine | HCID 67326 | — |
| Reactant | (1R,4R,6S)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane | HCID 86605347 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 11417932 | HCID 11417932 | — |
Reaction Steps
(1R, 4R, 6S)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane, 28c, (0.02 g, 0.075 mmol) was reacted with para-fluoro-benzylamine (0.19 g, 1.50 mmol) in ethanol (Procedure E) to yield (2R, 4S, 5S)-2-benzhydryl-5-(4-fluoro-benzylamino)-tetrahydropyran-4-ol, (+)-29b, 0.028 g (94%, [α]D-(+)77.6, c=1, MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915433B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-0255d73938ec43eaa570e050709fea12 |
| Source note | uspto-grants-2011_03 |