HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → (2R,4S,5S)-5-Azido-2-benzhydryl-tetrahydropyran-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | (2S,4R,5R)-5-Azido-2-benzhydryl-tetrahydro-pyran-4-ol | HCID 11716531 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2R,4S,5S)-5-Azido-2-benzhydryl-tetrahydropyran-4-ol | HCID 11681112 | — |
Reaction Steps
(1R, 4R, 7S)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane 8c (0.04 g, 0.15 mmol) was treated with NaN3 (0.05 g, 0.75 mmol) and NH4Cl (0.018 g, 0.33 mmol) (Procedure F) yielded (2R, 4S, 5S)-5-Azido-2-benzhydryl-tetrahydro-pyran-4-ol 30b, 0.04 g (95%, [α]D=(+)108, c=1, MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915433B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-89769c3537d24c4ea416d027efabb7be |
| Source note | uspto-grants-2011_03 |