HRID60708

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(=O)OC(C1CC1)[C@@H]1C[C@H](CC(=O)[O-])[C@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)O1

HCID137190217

未命名化合物

2 次

结构：CCC(OC(C)=O)[C@@H]1C[C@H](CC(=O)[O-])[C@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)O1

HCID137190218

未命名化合物

PRODUCTS

生成物

结构：Nc1nc2c(sc(=O)n2[C@@H]2O[C@H](C(O)C3CC3)C[C@H]2O)c(=O)[nH]1

HCID137108719

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to Example 1, by using [(2R,3R,5S)-5-[acetoxy(cyclopropyl)methyl]-2-(5-amino-2,7-dioxo-6H-thiazolo[4,5-d]pyrimidin-3-yl)tetrahydrofuran-3-yl]acetate (compound 14b) instead of [(2R,3R,5S)-5-(1-acetoxypropyl)-2-(5-amino-2,7-dioxo-6H-thiazolo[4,5-d]pyrimidin-3-yl)tetrahydrofuran-3-yl]acetate (compound 1g). Example 14 was purified and separated by preparative HPLC to afford Example 14-A and Example 14-B as white solid.

WORKUP

后处理

customExample 14 was purified
customseparated by preparative HPLC