4-Chloro-3-nitrophenol → HCID 60204757, compound

HRID 607165Notes

Reaction equation

HRID 607165 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].Br[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]([CH3:23])([CH3:22])[CH3:21])=[CH:16][CH:15]=1>>[C:20]([C:17]1[CH:16]=[CH:15][C:14]([CH2:13][O:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([N+:9]([O-:11])=[O:10])[CH:4]=2)=[CH:19][CH:18]=1)([CH3:23])([CH3:21])[CH3:22]

Participants

3

Reactant 2

HCID 691274-Chloro-3-nitrophenolHCID 878361-(Bromomethyl)-4-(1,1-dimethylethyl)benzene

Product 1

HCID 60204757HCID 60204757, compound

Procedure

A solution of 4-chloro-3-nitro-phenol was reacted with 1-Bromomethyl-4-tert-butyl-benzene using the conditions described in Example 10C to provide 4-(4-tert-Butyl-benzyloxy)-1-chloro-2-nitro-benzene which was treated sequentially using the procedures from Examples 10D and 10E to provide the title product.

Sources & evidence

ORD record
ord-0531b9d8bba84e08b58e2feeedde7cd8
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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