4-Bromobenzyl bromide → 4-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene

HRID 607168Notes

Reaction equation

HRID 607168 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19]Br)=[CH:15][CH:14]=1>>[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][O:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([N+:9]([O-:11])=[O:10])[CH:4]=2)=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 685274-Bromobenzyl bromideHCID 691274-Chloro-3-nitrophenol

Product 1

HCID 574698834-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene

Procedure

A solution of 4-chloro-3-nitro-phenol was reacted with 1-Bromo-4-bromomethyl-benzene using the conditions described in Example 10C to provide 4-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene which was treated sequentially using the procedures from Examples 10D and 10E to provide the title product.

Sources & evidence

ORD record
ord-f2d5bb5069cb405ba9b7e9635515c59d
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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