HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 66808423, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chloro-3-nitrophenol | HCID 69127 | — |
| Reactant | 1-Bromo-4-(1-bromoethyl)benzene | HCID 9838146 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 66808423 | HCID 66808423 | 92.2% |
Reaction Steps
The product from Example 22A (995 mg, 3.77 mmol) was reacted with 4-chloro-3-nitro-phenol (650 mg, 3.77 mmol) in 15 mL of DMF with K2CO3 (10.4 g, 3.77 mmol) at 80° C. for 3 h. Cooled to room temperature and diluted with water. Extracted with CH2Cl2, washed four times with water. Dried over Na2SO4, filtered and concentrated under vacuum giving the title compound (1.24 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915411B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-11ed1556b4f242c481a4b49ece88cf70 |
| Source note | uspto-grants-2011_03 |