HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 4-[2-Amino-4-(1-phenyl-ethoxy)-phenylsulfanyl]-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 4-{4-[1-(4-Bromo-phenyl)-ethoxy]-2-nitro-phenylsulfanyl}-phenol | HCID 66808220 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[2-Amino-4-(1-phenyl-ethoxy)-phenylsulfanyl]-phenol | HCID 66808439 | 104.1% |
Reaction Steps
The product from Example 22C (560 mg, 1.25 mmol) was reacted with Fe (279 mg, 5.0 mmol) and NH4Cl (76 mg, 1.40 mmol) in 5 mL MeOH/5 mL THF/2.5 mL water following the procedure from Example 10E giving the title compound as a solid (439 mg, 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915411B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-dd263af3d65e4d8985e2694af832d05a |
| Source note | uspto-grants-2011_03 |