4-Chloro-3-nitrophenol → HCID 57469887, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].Cl[CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:15]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:21])([F:22])[F:23])[CH:15]=2)=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]Participants
3
Procedure
A solution of 4-chloro-3-nitro-phenol was reacted with 1-Chloromethyl-3-trifluoromethyl-benzene using the conditions described in Example 10C to provide 1-Chloro-2-nitro-4-(3-trifluoromethyl-benzyloxy)-benzene which was treated sequentially using the procedures from Examples 10D and 10E to provide the title product.
Sources & evidence
- ORD record
- ord-8586e1ddc0054bbdadf4d1c2beb9a1ab
- Source dataset
- uspto-grants-2011_03
- Patent number
- US07915411B2
Reaction notes
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