3-Nitrophenol → HCID 16783749, compound

HRID 607291Notes

Reaction equation

HRID 607291 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)([O-])=O.[Br:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18]Br)[CH:13]=1.BrCC1C=CC=C(F)C=1>>[Br:11][C:12]1[CH:13]=[C:14]([CH:15]=[CH:16][CH:17]=1)[CH2:18][O:10][C:6]1[CH:5]=[C:4]([NH2:1])[CH:9]=[CH:8][CH:7]=1

Participants

4

Reactant 3

HCID 111373-NitrophenolHCID 680073-Fluorobenzyl bromideHCID 699793-Bromobenzyl bromide

Product 1

HCID 16783749HCID 16783749, compound

Procedure

3-Nitro-phenol was reacted with 1-bromo-3-bromomethyl-benzene according to the procedure from Example 199A substituting 1-bromo-3-bromomethyl-benzene for 1-bromomethyl-3-fluoro-benzene then reduced according to the procedure from Example 199B to provide the title compound.

Sources & evidence

ORD record
ord-633c62ad2dd7475f9a2ce323220d4eae
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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