3-Nitrophenol → HCID 20119514, compound

HRID 607292Notes

Reaction equation

HRID 607292 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)([O-])=O.Br[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=1.BrCC1C=CC=C(F)C=1>>[CH3:20][O:19][C:15]1[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=1)[CH2:12][O:10][C:6]1[CH:5]=[C:4]([NH2:1])[CH:9]=[CH:8][CH:7]=1

Participants

4

Reactant 3

HCID 111373-NitrophenolHCID 680073-Fluorobenzyl bromideHCID 40672073-Methoxybenzyl bromide

Product 1

HCID 20119514HCID 20119514, compound

Procedure

3-Nitro-phenol was reacted with 1-Bromomethyl-3-methoxy-benzene according to the procedure from Example 199A substituting 1-Bromomethyl-3-methoxy-benzene for 1-bromomethyl-3-fluoro-benzene then reduced according to the procedure from Example 199B to provide the title compound.

Sources & evidence

ORD record
ord-d2ccf65b2bfe41b2ab04f40a942e7bcd
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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